P270 do not eat, drink or smoke when using this product. S45 in case of accident or if you feel unwell seek medical advice immediately show the label. Safety data sheet product name lidocaine hydrochloride. Material safety data sheet hydrochloric acid section 1 chemical product and company identification msds name.
Search results for ticlopidine hydrochloride at sigmaaldrich. Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans. S26 in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. However, the results of one study atlast trial suggest that the frequency of stent thrombosis and other adverse ischemic events remains low even when ticlopidine is discontinued after 2 weeks of therapy. Ticlid ticlopidine hcl should be used only as directed by your doctor. Ticlopidinepmetabolism and the risk of toxicity of theophylline. Ticlopidine hydrochloride is metabo lized extensively by the liver, no intact ticlopidine hydrochloride is detected in the urine. On sdspage c, pai1 formed a covalent complex with tpa, whereas no pai1tpa. Sigmaaldrich offers a number of ticlopidine hydrochloride products. Hydrochloric acid, 10% vv safety data sheet according to federal register vol. Cimetidinepmetabolism of ticlopidine and may qthe risk of toxicity. Some people may have such side effects as diarrhea, skin rash, stomach or intestinal discomfort. Federal occupational safety and health administration standard 29 cfr 1910.
Side effects of ticlid ticlopidine hcl, warnings, uses. Ticlopidine hydrochloride supplier cas 53885351 tocris. Ticlopidine hydrochloride hazard statements h302 harmful if swallowed. Sarpogrelate hydrochloride may therefore maintain the cbf at a lower mbp than ticlopidine hydrochloride, even though the mbp reduction is about the same or greater. View and buy high purity ticlopidine hydrochloride from tocris bioscience. Product name ticlopidine hydrochloride sigmaaldrich. Hold eyelids apart and flush eyes with plenty of water for at. The objective of the current study was to develop a simple, precise and accurate spectrophometric assay method and validated for determination of ticlopidine hydrochloride in solid pharmaceutical dosage forms. Extreme high moderate low section 1 chemical product and company identification product name tizanidine hcl statement of hazardous nature considered a hazardous substance according to osha 29 cfr 1910. Chemical product and company identification manufacturer name and.
Ticlopidine inhibits liver cyp2c19 and cyp2b6 and thus can affect blood levels of medications metabolized by these systems. Hydrogen chloride hcl, nitrogen oxides nox, carbon monoxide co, carbon dioxide co2. Ticlid ticlopidine hydrochloride is a platelet aggregation inhibitor used to prevent blood clots after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels. Keep ticlid ticlopidine hcl out of reach of children. Page 7 of 9 msds dimethylformamide behaviorcentral nervous system convulsions, muscle weakness and oth er symptoms similar to that of acute ingestion, respiration dyspnea. Aspirinpotentiates the effect of ticlopidine on platelets concurrent usenotrecommended. State equivalent standards, and canadian workplace hazardous materials identification system standards cpr 4.
Safety data sheet according to federal register vol. As with most organic solids, fire is possible at elevated temperatures or. Material safety data sheet msds hexane section 1 product and company identification product product name. Ticlopidine hydrochloride 53885351 cayman chemical.
Identification of the substancemixture and of the companyundertaking 1. Identification of the substancemixture and of the companyundertaking. Ticlopidine hydrochloride monograph for professionals. Estrogens suppress a behavioral phenotype in zebrafish mutants of. Safety data sheet according to 29cfr19101200 and ghs rev. Hydrochloric acid, 37% ww safety data sheet according to federal register vol. Safety data sheet tris hydrochloride precautionary. This msds has been prepared according to the hazard criteria of the controlled products regulations cpr and the msds contains all of the information required by the cpr. Uranium phosphide reacts with hydrochloric acid to release spontaneously flammable phosphines. Clonidine hydrochloride safety data sheet supersedes revision. No test data on mobility of the components available.
Valve protection caps must remain in place unless container is secured with valve outlet piped to use point. Sds of ticlopidine hydrochloride, safety data sheets, cas. Download product insert pdfdownload safety data sheet sds pdf. Material safety data sheet of ticlopidine hydrochloride. Pdf a novel inhibitor of plasminogen activator inhibitor1 provides. Ticlopidine c14h14clns cid 5472 structure, chemical names, physical and. Pdf inhibition of plasminogen activator inhibitor pai1 is useful to treat several. If any of these problems are persistent, or if you are concerned. Material safety data sheet of ticlopidine hydrochloride contains identification of substance and details of the supplier of the safety data sheet. Keep in a tightly closed container, stored in a cooled, dry, ventilated area. In patients receiving an intracoronary stent, following successful stent implantation, ticlopidine therapy may be continued for up to 30 days. Rubidium acetylene carbides burns with slightly warm hydrochloric acid. As in any fire, wear a selfcontained breathing apparatus in pressuredemand, mshaniosh approved or equivalent, and full protective.
The students ttest, welchs ttest and the paired ttest were used. Precautionary statements p264 wash contaminated skin thoroughly after handling. India veritas house, 70 mint road, fort, mumbai 400 001. First aid measures description of first aid measures. Ticlopidine binds to the p2y12 receptor, preventing changes in the glycoprotein iibiiia conformation and suppressing fibrinogenplatelet binding. Ticlopidine is a first generation thienopyridine adpp2y12 receptor inhibitor that exhibits antithrombotic and cardioprotective activities. Lithium silicide in contact with hydrogen chloride becomes incandescent. Section 5 fire fighting measures general information. However, we make no warranty of merchantability or any other warranty, express or implied, with. Ticlopidine hydrochloride analytical standard, for drug analysis. Ticlopidine is a thienopyridine which, when metabolized by the body, irreversibly blocks the p2y12 component of the adp receptor on the surface of. Ticlopidine hydrochloride is an adenosine diphosphate adp receptor inhibitor against platelet aggregation with ic50 of 2. Ticlopidine hydrochloride safety data sheet section 2. Calcium carbide reacts with hydrogen chloride gas with incandescence.
Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. The first generic ticlopidine hydrochloride was fda approved in 1999. The mbp range associated with preservation of cbf depends on a balance between the contractility of resistant cerebral arteries and. It can cause gastrointestinal tract irritation with heartburn, abdominal pain, nausea, vomiting or diarrhea.
Doxorubicin hydrochloride solution for injection 2 mgml. A pvalue of hydrochloride n 31 or ticlopidine hydrochloride n 43. Adobe acrobat reader is required to reliably view, print and comment on pdf documents ticlopidine hydrochloride product citations see how others have used ticlopidine hydrochloride. Lidocaine hydrochloride and epinephrine injection 1. Used to reduce the risk of fatal or nonfatal thrombotic stroke in patients who have had either a previous completed thrombotic stroke or stroke precursors e. Unme tabolized ticlopidine hydrochloride is a minor component in plasma after a single dose, but at steady state, ticlopidine hydrochloride is the major component. December 15, 2003 sulfuric acid page 3 of 5 eu safety phrases.
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